Personalized medicine promises to tailor treatments to your genes, but I doubt the hype matches reality for most patients. My sister had a pharmacogenomic test that suggested a certain antidepressant, yet the drug still failed her after six weeks. While genetic markers help in oncology like HER2 or BRCA, the evidence for everyday conditions—depression, hypertension, diabetes—remains thin and inconsistent. Should we really be spending billions on genome sequencing when lifestyle changes and standard care often yield better outcomes?