After six years in biomedical research, I've noticed that CRISPR gene editing gets celebrated as a miracle tool, but I think we're glossing over its real-world limitations in treating complex diseases. We keep hearing about successful lab experiments, yet translating those results into effective therapies for patients has been painfully slow, and off-target effects remain a genuine safety concern. Should we be more cautious about pouring billions into CRISPR-based treatments when simpler approaches might achieve similar outcomes?